When starting out, make short throws and keep the disc's flight as flat as possible. The disc will react differently if released angled nose up or down, or angled side-to-side.
Until you become more skilled, its best to practice when the winds are calm. If you do practice in the wind, try to throw across the wind, not downwind or upwind. Once you become a proficient thrower, you may choose to throw into the wind for extra float time or with the wind at your back for longer distances.
At first, practice only short range throws (10 or 15 yards) that are released between waist and shoulder height. Gradually increase the distance of your throws as you gain proficiency.